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Search Results for " orphan disease "

6

Compounds

Cat No. Product Name Synonyms Targets
TN6715 7-Ketocholesterol Others
7-Ketocholesterol is a metabolite of Cholesterol
T60199 NCRW0005-F05 GPR
NCRW0005-F05 is a potent agonist of orphan G-protein coupled receptor GPR139 with an IC 50 value of 0.21 μM. NCRW0005-F05 can be used to research diabetes, obesity and Parkinson's disease [1].
TP1982L Neuropeptide S (Rat) acetate Neuropeptide Y Receptor
Neuropeptide S (Rat) acetate is an endogenous ligand of a previously orphan G-protein-coupled receptor now named NPS receptor. Neuropeptide S (Rat) acetate can be used for the research of nervous system disease [1].
T0755 Carglumic Acid Carbaglu,N-Carbamylglutamate,N-Carbamyl-L-glutamic acid,Carbamylglutamic acid,Carbamino-L-glutamic acid,Ureidoglutaric acid Others
Carglumic Acid (Ureidoglutaric acid) is an orphan drug used to treat hyperammonemia in patients with N-acetyl glutamate synthase absence. This rare hereditary disease results in elevated blood levels of ammonia, which ca...
T73545 TH470
TH470, a potent and highly selective inhibitor of LIM kinase 1/2 (LIMK1/2), demonstrates specificity with IC50 values of 9.8 nM for LIMK1 and 13 nM for LIMK2, making it applicable in orphan disease research.
T37187 D-erythro/L-threo Lysosphingomyelin (d18:1) D-erythro/L-threo Lysosphingomyelin (d18:1)
Lysosphingomyelin is an endogenous bioactive sphingolipid and a constituent of lipoproteins.1,2It is produced by the removal of the acyl group from sphingomyelin by a deacylase and acts as a precursor in the biosynthesis...
TargetMol